| Sagaia (aka Darius II) (3) |
| Saint Sword (2) |
| Samurai Shodown |
| Saturday Night Slam Masters |
| SeaQuest DSV |
| Sensible Soccer: European Champions |
| Shadow Blasters (2) |
| Shadow Dancer: The Secret of Shinobi (6) |
| Shadow of the Beast (5) |
| Shadow of the Beast 2 (2) |
| Shadow of the Beast II |
| Shadowrun (4) |
| Shining Force (3) |
| Shining Force 2 (3) |
| Shining in the Darkness (3) |
| Shinobi III: Return of the Ninja Master (5) |
| Shove It! ...The Warehouse Game |
| Side Pocket (2) |
| Simpsons: Bart vs. The Space Mutants, The (2) |
| Skeleton Krew |
| Skitchin' |
| Slap Fight MD |
| Slaughter Sport |
| Snow Bros. |
| Socket |
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